2014
DOI: 10.1016/j.homp.2013.08.004
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Experimental evidence of stable water nanostructures in extremely dilute solutions, at standard pressure and temperature

Abstract: This paper presents the results of several experimental methods (FT-IR spectroscopy, UV-vis spectroscopy, fluorescence microscopy (FM), Atomic Force Microscopy (AFM)) evidencing structural changes induced in extremely diluted solutions (EDS), which are prepared by an iterated process of centesimal (1:100) dilution and succussion (shaking). The iteration is repeated until an extremely high dilution is reached, so that the composition of the solution becomes identical to that of the solvent--in this case water--… Show more

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Cited by 79 publications
(92 citation statements)
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“…Numerous methods have demonstrated that "high dilutions" differ structurally from the intact solvent. These methods have included conductometry [9,10], pH monitoring [9,10], viscometry [10], calorimetry [9], photoluminescence spectroscopy [11], ultraviolet-visible spectrophotometry [12][13][14], fluorescence microscopy [12], atomic force microscopy [12], infrared spectroscopy [12], Raman spectroscopy [15,16], nuclear magnetic resonance (NMR) relaxometry [17][18][19][20], electromagnetic signal detection [21], crystallogenesis studies [22], droplet crystallization [23], NMR spectroscopy [20,24], and dielectric property analysis [25,26]. On the basis of these results, a popular perception of the solvent "memory" effect has been formed-the dilutions contain a structured material (dynamic) matrix, which retains information about the eliminated original substance.…”
Section: Introductionmentioning
confidence: 99%
“…Numerous methods have demonstrated that "high dilutions" differ structurally from the intact solvent. These methods have included conductometry [9,10], pH monitoring [9,10], viscometry [10], calorimetry [9], photoluminescence spectroscopy [11], ultraviolet-visible spectrophotometry [12][13][14], fluorescence microscopy [12], atomic force microscopy [12], infrared spectroscopy [12], Raman spectroscopy [15,16], nuclear magnetic resonance (NMR) relaxometry [17][18][19][20], electromagnetic signal detection [21], crystallogenesis studies [22], droplet crystallization [23], NMR spectroscopy [20,24], and dielectric property analysis [25,26]. On the basis of these results, a popular perception of the solvent "memory" effect has been formed-the dilutions contain a structured material (dynamic) matrix, which retains information about the eliminated original substance.…”
Section: Introductionmentioning
confidence: 99%
“…It is corroborated by investigations concerning the physicochemical properties of water subjected to physical perturbations like Iteratively Nafionated Water (INW) [33][34][35], Iteratively Filtered Water (IFW) [35][36][37][38], Extremely Diluted Solutions (EDS) [39][40][41][42][43][44] and effect of hydrophilic surfaces [45][46][47][48][49]. Ref [47][48][49] also suggest changes in structure of water.…”
Section: Acceptance Criteria Of Workmentioning
confidence: 86%
“…Ref [47][48][49] also suggest changes in structure of water. These are direct or indirect evidences for existence of Coherent Domains (CD) in water.…”
Section: Acceptance Criteria Of Workmentioning
confidence: 99%
“…Its possible explanation is offered in ref [9] in terms of structures. Latest support to structural model comes from the work of Elia V et al [20]. The structural model may be at its infancy due to limited data in its support.…”
Section: Supports For Structural Conceptmentioning
confidence: 99%