Experimental in vitro transmission of<i>Babesia</i>sp. (EU1) by<i>Ixodes ricinus</i>

Bonnet, Sarah; Brisseau, Nadine; Hermouet, Axelle; Jouglin, Maggy; Chauvin, Alain

doi:10.1051/vetres/2009004

Cited by 50 publications

(36 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This tick has also been shown to be a competent vector for Babesia sp. strain EU-1 (7,9). Roe deer appear to be the wild reservoir host for EU-1, but other reservoir hosts may exist that have not been identified (10).…”

Section: Routes Of Transmissionmentioning

confidence: 99%

Transfusion-TransmittedBabesiaspp.: Bull's-Eye onBabesia microti

2011

View full text Add to dashboard Cite

SUMMARY Babesia spp. are intraerythrocytic protozoan parasites of animals and humans that cause babesiosis, a zoonotic disease transmitted primarily by tick vectors. Although a variety of species or types of Babesia have been described in the literature as causing infection in humans, the rodent parasite Babesia microti has emerged as the focal point of human disease, especially in the United States. Not only has B. microti become established as a public health concern, this agent is increasingly being transmitted by blood transfusion: estimates suggest that between 70 and 100 cases of transfusion-transmitted Babesia (TTB) have occurred over the last 30 years. A recent upsurge in TTB cases attributable to B. microti , coupled with at least 12 fatalities in transfusion recipients diagnosed with babesiosis, has elevated TTB to a key policy issue in transfusion medicine. Despite clarity on a need to mitigate transmission risk, few options are currently available to prevent the transmission of B. microti by blood transfusion. Future mitigation efforts may stress serological screening of blood donors in regionalized areas of endemicity, with adjunct nucleic acid testing during the summer months, when acute infections are prevalent. However, several hurdles remain, including the absence of a licensed blood screening assay and a thorough cost-benefit analysis of proposed interventions. Despite current obstacles, continued discussion of TTB without proactive intervention is no longer a viable alternative.

show abstract

Section: Routes Of Transmissionmentioning

confidence: 99%

Transfusion-TransmittedBabesiaspp.: Bull's-Eye onBabesia microti

2011

View full text Add to dashboard Cite

show abstract

“…Another large branch consists of the Babesia species that parasitize cattle (Babesia major and B. bigemina) and small ruminants (Babesia crassa and Babesia motasi). The ticks of the genus Ixodes are the major vectors of B. divergens, B. capreoli, B. odocoilei, and B. venatorum (Zintl et al, 2003;Becker et al, 2009;Bonnet et al, 2009;Gray et al, 2010), while the remaining Babesia species are mainly transmitted by ticks belonging to the genera Haemaphysalis, Dermacentor, Hyalomma, Rhipicephalus, etc. (Schnittger et al, 2003;Hunfeld et al, 2008).…”

Section: Introductionmentioning

confidence: 99%

Genetic variability of Babesia parasites in Haemaphysalis spp. and Ixodes persulcatus ticks in the Baikal region and Far East of Russia

Рар

Epikhina

Suntsova

et al. 2014

Infection, Genetics and Evolution

View full text Add to dashboard Cite

“…and bacteria within the genus Anaplasma, respectively. Ixodes ricinus, the most prevalent tick species in northern and western Europe, is an important vector of both these pathogens (Baumgarten et al 1999;Becker et al 2009;Bonnet et al 2009). …”

Section: Introductionmentioning

confidence: 99%

Longitudinal field study on bovine Babesia spp. and Anaplasma phagocytophilum infections during a grazing season in Belgium

Lempereur

Lebrun²,

Cuvelier³

et al. 2011

Parasitol Res

View full text Add to dashboard Cite

Anaplasmosis and babesiosis are major tick-borne diseases with a high economic impact but are also a public health concern. Blood samples collected in the spring, summer, and autumn of 2010 from 65 cows in seven different farms in Belgium were monitored with an indirect immunofluorescence antibody test to assess seroprevalence against these pathogens. Seroprevalences to Babesia spp. were measured as 10.7%, 20%, and 12.3% in spring, summer, and autumn, respectively, whereas seroprevalences to Anaplasma phagocytophilum were 30.8%, 77%, and 56.9%, respectively. A total of 805 Ixodes ricinus ticks were collected at the same time from both cattle (feeding ticks) and grazed pastures (questing ticks). The infection level of ticks, assessed by PCR assay, for Babesia spp. DNA was 14.6% and 7.9% in feeding and questing ticks, respectively, whereas 21.7% and 3% of feeding and questing ticks were found be positive for A. phagocytophilum cDNA. Fifty-five PCR-positive samples were identified by sequencing as Babesia sp. EU1, of which five from feeding ticks were positive for both A. phagocytophilum and Babesia sp. EU1. The high density of wild cervids in the study area could explain these observations, as deer are considered to be the main hosts for adults of I. ricinus. However, the absence of Babesia divergens both in feeding and questing ticks is surprising, as the study area is known to be endemic for cattle babesiosis. Increasing cervid populations and comorbidity could play an import role in the epidemiology of these tickborne diseases.

show abstract

Experimental in vitro transmission ofBabesiasp. (EU1) byIxodes ricinus

Cited by 50 publications

References 25 publications

Transfusion-TransmittedBabesiaspp.: Bull's-Eye onBabesia microti

Transfusion-TransmittedBabesiaspp.: Bull's-Eye onBabesia microti

Genetic variability of Babesia parasites in Haemaphysalis spp. and Ixodes persulcatus ticks in the Baikal region and Far East of Russia

Longitudinal field study on bovine Babesia spp. and Anaplasma phagocytophilum infections during a grazing season in Belgium

Contact Info

Product

Resources

About