Experimental infection of a lamb with Cryptosporidium parvumgenotype 1

Occurrence of Cryptosporidium hominis in pigeons (Columba livia)

“…Most studies have found that C. hominis oocysts are not infective for cattle, mice, rats, cats or dogs. There have been few reports of non-human infections with C. hominis, dugongs (D. dugon) , lambs (Giles et al 2001), and cattle (Smith et al 2005). However, the rest of the reports about C. hominis infections have been confined to humans and primates (Xiao et al 1999b).…”

Infectivity of Cryptosporidium parvum genotype I in conventionally reared piglets and lambs

“…However, interpretation of these studies was difficult because all the experiments were established without prior determination of the isolate's genotype. Recently, C. parvum genotype I was successfully propagated in gnotobiotic piglets (Widmer et al 2000) and in a lamb (Giles et al 2001).…”

“…Despite the improvement of in vitro cultivation of C. parvum (Hijjawi et al 2001), mass production of oocysts depends on animal inoculation (Petry et al 1995). Recently, experimental infection of C. parvum genotype I in gnotobiotic piglets and in a lamb was reported (Widmer et al 2000;Giles et al 2001).…”

Infectivity of Cryptosporidium hominis and Cryptosporidium parvum Genotype 2 Isolates in Immunosuppressed Mongolian Gerbils

“…In humans, the most commonly detected genotypes are Cryptosporidium hominis (i.e., C. parvum genotype 1 recognized as a distinct species) and the bovine C. parvum genotype 2 (23,38). C. hominis naturally infects humans almost exclusively, and experimentally, C. hominis infections were obtained in calves, lambs, and pigs with at least some isolates but not in rodents commonly used for propagating C. parvum genotype 2, with some exceptions (2,3,13,14,32,38,40). In spite of recent advances, the pathogenesis of cryptosporidiosis is presently poorly understood, and a limited number of effective anticryptosporidial therapeutic agents is available.…”