With prospective flight speeds exceeding Mach 12, airbreathing scramjets, incorporated in hybrid satellite launch vehicles, offer efficiency and operability benefits when compared to rocket-based systems. By capturing atmospheric air, the scramjet second stage negates the requirement for onboard oxidisers. Addressing the small satellite niche market, these hybrid systems provide a cost-effective solution to launching such payloads to orbit. At hypersonic speeds, however, conventional wing-mounted engine nacelles are not viable; the scramjet must be integrated to the airframe. Hence, the flight-candidate, Mach 12 Rectangular-to-Elliptical Shape-Transitioning (M12REST) scramjet blends a rectangular capture area (permitting parallel mounting of engine modules to the planar vehicle underside), with a structurally efficient elliptical combustor. As access-to-space scramjets suffer immense heating loads, and engine airflow residence times approach air-fuel reaction timescales, hydrogen fuel is utilised for its exceptional cooling capacity and rapid ignition characteristics. However, efficient fuelling techniques are required to avoid crippling the engine's performance through conservative combustor lengths. This thesis numerically and experimentally investigated whether the performance of such an airframe-integrated scramjet can be sufficiently enhanced through customisation of fuel injection and combustor geometry to achieve net thrust at Mach 12. Three-dimensional, chemically reacting Reynolds-averaged Navier-Stokes solutions enabled numerical analysis, while experimental validation was performed within The University of Queensland's, T4 Stalker Tube.Preliminary work investigated cascaded fuel injectors, targeting mixing and penetration improvements. Two streamwise-aligned jets were employed, with the upstream injector half the diameter of the rear, while the distance between each was varied. The upstream jet induced a low dynamic pressure region in its wake, shielding the downstream jet from the hypersonic crossflow. The leeward jet benefits from an increased local jet-to-freestream momentum ratio, while its larger diameter increases absolute penetration. Examining performance at M12REST mean combustor entrance conditions, unique optimal injector spacings existed for each performance metric, displaying improved penetration, spread, and mixing across the range of flight Mach numbers examined (6 ≤ M ≤ 12). However, jet-to-jet spacings of 4-6 total jet diameters displayed universal performance enhancements over single fuel jets. With penetration improvements of 30-40%, and mixing improvements of 40-70%, the simple fixed geometry, passive technique is ideal for use within an accelerating access-to-space scramjet.While cascaded injectors improved performance within uniform flows, the flows ingested by airframe-integrated scramjets are far less homogeneous. Non-uniform compression fields combine with thick boundary layers developed over the vehicle forebody to deliver density stratified flow to the combustor. This thesis ...