a b s t r a c tThe increasing need for thermal comfort has led to a rapid increase in the use of cooling systems and, consequently, electricity demand for air-conditioning systems in buildings. Heat-driven ejector refrigeration systems appear to be a promising alternative to the traditional compressor-based refrigeration technologies for energy consumption reduction. This paper presents a comprehensive literature review on ejector refrigeration systems and working fluids. It deeply analyzes ejector technology and behavior, refrigerant properties and their influence over ejector performance and all of the ejector refrigeration technologies, with a focus on past, present and future trends. The review is structured in four parts. In the first part, ejector technology is described. In the second part, a detailed description of the refrigerant properties and their influence over ejector performance is presented. In the third part, a review focused on the main jet refrigeration cycles is proposed, and the ejector refrigeration systems are reported and categorized. Finally, an overview over all ejector technologies, the relationship among the working fluids and the ejector performance, with a focus on past, present and future trends, is presented.