A harmonic response analysis was conducted on semi-hermetic refrigeration compressor by Abaqus software. The vibration displacement and acceleration response spectrums of the compressor’s key points were obtained. The vibration characteristics of the compressor show that the harmonic response analysis result is consistent with the experimental one. The vibration of the compressor at 50Hz is the most dramatic. The first trough in each direction is found around 70Hz, and after that each direction’s acceleration goes up significantly. At the same time, the conclusion verifies the vibration of compressor’s bottom corners by LMS Test. Lab Signature Testing. The paper provides a scientific reference for the further study on vibration and noise reduction in food refrigeration compressors.