Machining operation and presence of water droplet cause increasing the surface roughness of wet steam ejector walls and changing its performance in the refrigeration cycle. The purpose of this work is to investigate the influences of the primary nozzle surface roughness on wet steam ejectors in the refrigeration cycle with steam water as a working flow. The flow is modeled by solving governed equations based on the Eulerian-Eulerian approach. The proposed model is validated by comparison numerical results with experimental data of the ejector and nozzle. Moreover, different surface roughness has been successfully applied to the primary nozzle and its effect on the entire flow is shown. Six properties of wet steam are selected, including pressure, temperature, Mach number, droplet average radius, droplet growth rate, and liquid mass fraction. The result shows, increase in the surface roughness resulted in a shift of the shock chain to the primary nozzle, damping shock strength, and increasing temperature in the diffuser. In addition, increment of the primary nozzle surface roughness decreases ER and COP of the refrigeration cycle by 3.67% and 3.8%, respectively. According to the important impact of the roughness on the liquid mass fraction, droplet average radius, droplet growth rate, ER, and COP, designers and operators should be considered the roughness effects in the design and operation of wet steam ejectors.