“…A great variety of seizure models and SE models have been developed over the years in the immature brain, to investigate the higher incidence of seizures observed in infants, as well as define the differences in SE between infants and adults in humans 64,82,83 . Specific models of induced seizures and SE in this section include the kainate model of SE [84][85][86] , the pilocarpine-induced SE [87][88][89] , the NMDA-induced SE 71,74,75 , the pentylenetetrazol (PTZ) model 32,[90][91][92] , and flurothyl-ind uced seizures 93 .…”