2015
DOI: 10.1118/1.4935865
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Experimental observation of acoustic emissions generated by a pulsed proton beam from a hospital‐based clinical cyclotron

Abstract: Purpose: To measure the acoustic signal generated by a pulsed proton spill from a hospital-based clinical cyclotron. Methods: An electronic function generator modulated the IBA C230 isochronous cyclotron to create a pulsed proton beam. The acoustic emissions generated by the proton beam were measured in water using a hydrophone. The acoustic measurements were repeated with increasing proton current and increasing distance between detector and beam. Results: The cyclotron generated proton spills with rise times… Show more

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Cited by 62 publications
(82 citation statements)
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“…In addition to the aforementioned approaches, in vivo range/dose verification utilizing proton‐induced acoustic (protoacoustic) signals is a very promising alternative solution. Since the concept was initially proposed by Askaryan, many groups have worked on a number of aspects including both numerical simulations and experimental measurements . Sulak et al experimentally detected acoustic signals produced by proton beams in fluid media and successfully demonstrated a thermal expansion model for this phenomenon .…”
Section: Introductionmentioning
confidence: 99%
“…In addition to the aforementioned approaches, in vivo range/dose verification utilizing proton‐induced acoustic (protoacoustic) signals is a very promising alternative solution. Since the concept was initially proposed by Askaryan, many groups have worked on a number of aspects including both numerical simulations and experimental measurements . Sulak et al experimentally detected acoustic signals produced by proton beams in fluid media and successfully demonstrated a thermal expansion model for this phenomenon .…”
Section: Introductionmentioning
confidence: 99%
“…The newest clinical sources, synchrocyclotrons, clinically deliver approximately 3.5 μs FWHM Gaussian proton pulses, which are predicted to be ideal for acoustic wave generation . To experimentally characterize proton‐induced thermoacoustics, researchers have first used accessible non‐clinical proton sources, and modified others . To generate detectable acoustic signals using a clinical IBA 230 cyclotron, Jones et al .…”
Section: Proton Therapy Range Verificationmentioning
confidence: 99%
“…62 To experimentally characterize proton-induced thermoacoustics, researchers have first used accessible nonclinical proton sources, 64,65 and modified others. 66 To generate detectable acoustic signals using a clinical IBA 230 cyclotron, Jones et al modified the proton pulse output by modulating the proton current entering the cyclotron with a function generator. 66 With this method, they were able to generate approximately Gaussian proton pulses of roughly 17 ls FWHM, and the arrival times of the hydrophonedetected pressure waves were proportional to detector distance from the beam.…”
Section: B Recent Workmentioning
confidence: 99%
“…In pencil beam scanning mode, macro pulses with a minimal duration of 1 ms are delivered. The pulse duration in double scattering mode is more than 20 ms. 1 The beam of the recently clinically introduced synchrocyclotron S2C2 of IBA has a different time structure with 7 µs pulse duration. 2 In preclinical studies, other time structures of the proton beam are also used, e.g., a modulated cyclotron C230 beam with pulse durations of about 20 µs.…”
Section: Introductionmentioning
confidence: 99%
“…2 In preclinical studies, other time structures of the proton beam are also used, e.g., a modulated cyclotron C230 beam with pulse durations of about 20 µs. 1 Furthermore, new accelerator technologies like laser plasma accelerators are under development to be introduced in therapy facilities. These laser accelerators deliver very short particle pulses with a pulse duration of few ps and low pulse repetition frequency of few Hz, i.e., pulse spacing of few hundred ms. 3 To limit the irradiation time to an acceptable maximum value, a high pulse dose in the order of 100 mGy is required.…”
Section: Introductionmentioning
confidence: 99%