“…In clinical and experimental studies of pain perception, it has been found that increasing anxiety is often associated with reports of increased pain. 15,16 This relationship is explained by the activation of the adrenergic system. Acute anxiety activates the sympathetic nervous system to relay a neural signal via the hypothalamus to stimulate preganglionic release of the neurotransmitter acetylcholine.…”
According to this study, preprocedure anxiety levels have an effect on postoperative pain scores in women undergoing HSG procedure. Multiparity, male operator, and higher preprocedure anxiety scores also may have an effect on postoperative pain scores.
“…In clinical and experimental studies of pain perception, it has been found that increasing anxiety is often associated with reports of increased pain. 15,16 This relationship is explained by the activation of the adrenergic system. Acute anxiety activates the sympathetic nervous system to relay a neural signal via the hypothalamus to stimulate preganglionic release of the neurotransmitter acetylcholine.…”
According to this study, preprocedure anxiety levels have an effect on postoperative pain scores in women undergoing HSG procedure. Multiparity, male operator, and higher preprocedure anxiety scores also may have an effect on postoperative pain scores.
“…State anxiety was assessed through the State Trait Anxiety Inventory -Form Y (Spielberger et al, 1983;Zachariae et al, 2001). This subscale has 20 items measuring anxiety at the moment of response in a 4-point Likert scale, with higher scores indicating higher state anxiety symptoms.…”
“…In a recent paper by Asbury et al the definition of syndrome X was "patients aged < 80 years with chest pain, positive exercise test for myocardial ischemia and angiographically smooth coronary arteries" [1]. On the other hands, Zachariae et al defined "normal coronary arteries" as "no significant coronary artery stenosis (< 50% luminal narrowing)" [47]. Clearly, with this definition, patients with normal angiography are diluted with those with mild coronary artery disease (CAD) in whom development of subsequent coronary events may simply reflect complication of CAD that was already present.…”
The term "chest pain with normal coronary arteries" encompasses a large number of different cardiac pathophysiological abnormalities, including impairment of coronary flow reserve, endothelial dysfunction, and early atherosclerosis that, in most cases, cannot be readily differentiated one from the other. To study early coronary atherosclerosis, physicians must look beyond contrast filled arteries (so called lumenology). Angiograms cannot evaluate the vessel wall, plaque distribution and composition or other morphology. Plaques are often angiographically not visible due to their small size and compensatory enlargement (outward remodeling) of the coronary arteries. As a result, the search for an underlying atherosclerotic process remains ongoing. Available clinical studies showed that many patients with chest pain and normal angiography have early atherosclerosis as documented by intravascular ultrasound imaging, reduced coronary flow reserve and coronary endothelial dysfunction. Additional studies showed that patients presenting with normal coronary angiography have recurrent coronary events at long-term follow up. Research to determine if improved diagnosis and treatment of quantitatively low degrees of atherosclerosis lead to improved outcomes of patients with normal angiography should be undertaken.
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