The manipulation of quantum coherence is one of the principal issues in the resource theory of coherence, with two critical topics being the purification and enhancement of coherence. Here, we present two no-go theorems for the deterministic purification of coherence and the probabilistic enhancement of coherence, respectively. Specifically, we prove that a quantum state cannot be deterministically purified if it can be expressed as a convex combination of an incoherent state and a coherent state. Besides, we give an easy-toverified sufficient and necessary condition to determine whether a state can be probabilistically enhanced via a stochastic strictly incoherent operation (sSIO). Our findings provide two feasibility criteria for the deterministic purification and the probabilistic enhancement of coherence, respectively. These results have repercussions on the understanding of quantum coherence in real quantum systems.