One of the main factors in the poultry house is maintaining a standardized microclimate. The quality of the product output in the final result depends precisely on the quality indicators of the air parameters. Poultry during its maintenance requires significant efforts and technological solutions. In this regard, authors improved microclimate system in air environment of the poultry house by installing exhaust fans on the side wall in a total number of 8 units. CFD modeling using ANSYS Fluent is a powerful tool for predicting the air flow scheme in a poultry house and is considered an alternative to experimental studies. Based on the obtained results of CFD modeling, it was established that the valves located at a height of 330 mm from the ceiling work most efficiently. Pressure drop for the inlet valves is 45.85 Pa. Air velocity at the inlet of the supply valves is equal to 9.17 m/s. Air velocity at a height of 0.7 m from the floor level varies within 0.57 m/s, the temperature is 9.91 °С.