“…Compliance with these requirements allows the elaboration of the plan and the execution of the experiment that provides the ability to detect the real effects of treatment factors. This article is based on the contributions of Fisher [1,2], Yates [3,4,5], Silva [6,7,8,9], Bailey [10], Cochran & Cox [11], Fisher & Yates [12] and Kuehl [13], which are explicitly referred in the text, and Cox [14], Christensen [15], Federer [16], Giesbrecht [17], Gould [18], Hinkelmann & Kempthorne [19], Kempthorne [20,21,22], Little & Hills [23], Mead [24], Mitchell &, Jolley [25], Pearce [26,27], Petersen [28], Selwyn [29], Shadish, Cook & Campbell [30].…”