Experimental studies on caffeine mediated synthesis of hydroxyapatite nanorods and their characterization

Abstract

Hydroxyapatite nanorods (HA) were fabricated using caffeine as a modifier at room temperature. Various concentrations of caffeine were utilized to synthesize the HA nanoparticles to analyze its effect on size, shape and morphology. The formation of phosphate ion was confirmed by Fourier Transform spectrophotometer (FTIR). Crystalline structure and phase of the nanoparticles was confirmed by x-ray diffraction study (XRD). The formation of HA nanorods with diversified morphology was confirmed by Transmission Electron Microscope (TEM) images. The results acquired in this study reveals that the HA nanoparticles synthesized using caffeine are uniform and evenly scattered nanorods. The average size of the nanorods obtained from the XRD study was in the range of 20-30 nm. The TEM and SAED investigation revealed the shape, morphology and arrangement of HA nanorods with higher crystallinity. This investigation claims that caffeine is a natural modifier to produce HA nanorods.

Synthesis and Characterization of Naringin Functionalized Nano-Hydroxyapatite for Bone Tissue Engineering

“…The SAED pattern obtained [ Figure 2a and 2b ] showed the crystalline nature with the formation of bright spot and well defined bands confirming the attributes of nanorange particles. [ 16 ] Also, the addition of Naringin did not alter the crystalline nature of HA nanoparticles.…”

Greening up organic reactions with caffeine: applications, recent developments, and future directions

“…Subramanian and co-workers 72 have explored the potential of caffeine as an organic modifier in the synthesis of hydroxyapatite (HA) nanorods. HA nanorods with high crystallinity with well-defined shapes were formed as conformed by FT-IR, X-ray diffraction studies, and TEM image analysis.…”

Effect of Aging Time and Sonication Treatment on Hydroxyapatite Structure from Limestone

“…HAp nanoparticles have been studied extensively for their excellent applications in biomedicine, especially in bone and dental tissue engineering [1,2]. HAp is a calcium phosphate hydrate with the chemical formula Ca10(PO4)6(OH)2 from the apatite mineral group [3].…”