Experimental Studies on the Cerebral Circulation

Recent studies have provided evidence of the relevance of pulsatility and hypertension in the following areas: (i) pressure and flow pulsatility and regulation of cerebral blood flow, (ii) cerebral and systemic haemodynamics, hypertension and brain pathologies (cognitive impairment, dementia, Alzheimer's disease), (iii) stroke and cerebral small vessel disease, (iv) cerebral haemodynamics and noninvasive estimation of cerebral vascular impedance, (v) cerebral and systemic pulsatile haemodynamics and intracranial pressure, (iv) response of brain endothelial cells to cyclic mechanical stretch and increase in amyloid burden. Studies to date, producing increasing epidemiological, clinical and experimental evidence, suggest a potentially significant role of systemic haemodynamic pulsatility on structure and function of the brain.

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Experimental Studies on the Cerebral Circulation

Cited by 4 publications

References 6 publications

Cerebral Hemodynamics in Preeclampsia and Eclampsia

Cerebral Hemodynamics in Preeclampsia and Eclampsia

Electron Microscopic Study of Arterial Lesions in Experimental Hypertension

Cerebral Haemodynamics: Effects of Systemic Arterial Pulsatile Function and Hypertension

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