Ti-6Al-4V alloy and commercially pure aluminum, which are commonly used in aerospace, medical, and automotive industries, are bonded by diffusion welding. Different welding parameters (560, 600, and 640 • C-0, 45, and 60 min-under argon shielding) are used in this process to make the materials more applicable in the industry. Here, the effects of parameters on the strength of joints were studied. The bonded samples were subjected to microhardness and tensile tests in order to determine their interfacial strength. The hardness values were found to decrease with increasing distance from the interface on the titanium side while it remained constant on the aluminum side. Maximum tensile strength was taken from the maximum bonding temperatures of 600 and 640 • C. A morphology examination of the diffusion interfaces was carried out with scanning electron microscopy.