This article assesses the potential of using a diamond-like carbon coating doped with tungsten, a-C:H:W (WC/C), on the sliding pairs of refrigeration compressors. The ability of WC/C coating to provide low wear and a low coefficient of friction was experimentally verified in a specific refrigeration compressor operating environment (lubrication with oil diluted with refrigerant) and under extreme operating conditions (starved lubrication with a small amount of oil). Conditions of starved lubrication with a substance of reduced lubricity promote a temperature increase and high mechanical (friction) stresses on the surface of the sliding pairs. These situations can hinder the effective operation of WC/C coatings. Comparative wear tests were carried out for S235JR steel samples with and without WC/C coating. It was found that the samples with the WC/C coating had the lowest wear values and the lowest friction coefficients (approximately 0.06). A low coefficient of friction suggests that even a small amount of oil (one drop) is likely sufficient to achieve mixed lubrication conditions between the tested sliding surfaces and reduce material loss. The tested WC/C coating can protect sliding friction pairs in refrigeration compressors under extreme operating conditions caused by a lack of oil. Less friction reduces the need for energy to drive the refrigeration compressor. Additionally, the significance of this research is highlighted by the fact that the wear tests were conducted using R452A, a novel, eco-friendly refrigerant.