hase-change phenomena play an important role in our daily life. They are of great interest for cooling electronic components or engines. They are also used in vapour generators. At least two thirds of the electrical energy produced in the world uses this technique. Two-phase flows are also present in space applications: energy production, electronic cooling devices and, as one can expect in the future, in waste water treatment and life support systems for long-duration space exploration missions. So, in many applications high heat fluxes are achieved by utilising the latent heat associated with the phase change from liquid to vapour. However, the physical mechanisms involved are intricate and many questions remain unanswered: how does a bubble nucleate on a heated surface? When will bubbles completely cover a hot surface? What is the amount of heat transferred by boiling evaporation or reversely, by condensation?The field clearly is at the crossroads of thermodynamics, fluid dynamics, materials sciences and physical chemistry of interfaces. Because of the complexity of the coupling effects in systems involving phase change and the lack of reliable prediction capabilities, the development of industrial devices is essentially based on empirical rules. Their utilisation then relies on correlations established between operational parameters and heat transfer performances, which cover a limited range of parameters and thus cannot be extrapolated to other situations and in particular to a microgravity environment.Progress in the field requires a better understanding of the basic mechanisms and the development of predictive capabilities. This is supported by recent advances in measurement techniques and an increase in computing performances. It is however still difficult, if not impossible to discriminate between these individual basic phenomena.Phase change occurs at interfaces, the boundaries separating different phases. Although molecularly thin, liquid-gas interfaces play a major role in the overall behaviour of the system. It is therefore crucial to understand the details of their static and dynamic behaviour. Because of the principle of minimal surface energy, an interface ideally tends to assume a spherical shape. However, on Earth, the gradient of hydrostatic pressure leads to the flattening of drops and elongation of bubbles. In a flow, viscous and inertia effects are also responsible for pressure gradients and thereby, for interface deformation. In liquid-vapour flows, the density difference is very high and gravity effects dominate capillary and viscous effects. Gravity generates thermal convection and causes bubble detachment during boiling and stabilises liquid films. Under normal gravity it is thus impossible to separate the various mechanisms involved.Microgravity is a good tool to improve the quantitative understanding of these physical mechanisms. Experiments have been performed in free-fall conditions at different time scales demonstrating the relevance of two-phase flow studies in space. Several inst...