Experimental Study of Rupture Pressure and Elasticity of Abdominal Aortic Aneurysms Found at Autopsy

Gomes, Vivian Carla; Raghavan, Madhavan L.; Silva, Luiz Fernando Ferraz da; Gomes, Jorge; Silvestre, Gina Camillo; Queiroz, Alexandre; Marques, Michele Alberto; Zyngier, Szulim Ber; Chung, Timothy K.; Silva, Erasmo Simão da

doi:10.1016/j.avsg.2020.08.111

Cited by 10 publications

(4 citation statements)

References 16 publications

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“…Prior studies report the prevalence of this disease as being higher in men (3.9%-7.2%) than in women (1%-1.3%), 1 more specifically among white male patients older than 65 years who have ever smoked. 1,2 Abdominal aortic aneurysm is described as the 10th cause of death in this demographic group, 3 and a study of risk factors analysis estimates the prevalence of the disease of being around 1 million people in the United States. 4 Abdominal aortic aneurysms are particularly rare in children, and are usually diagnosed in this age group in the context of connective tissue disorders, genetic mutations, infections (mycotic aneurysms), or vasculitis.…”

Section: Introductionmentioning

confidence: 99%

“…Prior studies report the prevalence of this disease as being higher in men (3.9%–7.2%) than in women (1%–1.3%), 1 more specifically among white male patients older than 65 years who have ever smoked. 1,2 Abdominal aortic aneurysm is described as the 10th cause of death in this demographic group, 3 and a study of risk factors analysis estimates the prevalence of the disease of being around 1 million people in the United States. 4…”

Section: Introductionmentioning

confidence: 99%

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Rare Case of Abdominal Aortic and Multiple Visceral Aneurysms in a Pediatric Patient With PIK3CA Mutation and Vasculitis

Gomes,

Parodi,

Wood

et al. 2023

Vasc Endovascular Surg

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Abdominal aortic aneurysms (AAA) are most commonly observed in elderly male patients and are particularly rare in children. Among the pediatric population, they are usually diagnosed in the context of connective tissue disorders, genetic mutations, or vasculitis. The same is true of visceral arteries aneurysms. This case report describes the staged management of an 11-year-old patient presenting PIK3CA mutation and a 5.8 cm infrarenal AAA associated with bilateral common iliac arteries and multiple visceral aneurysms, the largest observed in the superior mesenteric artery (SMA = 3.2 cm). After careful evaluation, decision was made to first approach the most life-threatening lesion (the infrarenal AAA due to the large diameter) and the remaining aneurysms in secondary procedures, with special attention to the SMA aneurysm. The patient underwent a staged repair, with the first phase consisting of an aortobi-iliac graft with the distal anastomosis made at the left common iliac artery and right external iliac artery. The right hypogastric artery was ligated. The second procedure consisted of SMA aneurysm repair with a plication technique, as 7 branches were visualized coming off the aneurysm sac. Postoperative pathology analysis of the aortic and SMA aneurysms sac revealed vasculitis with a mixed inflammatory pattern and a COL3A1 gene heterozygote variant. He is currently in his 18th month after the last surgical intervention, receiving immunomodulatory therapy, with a planned follow-up by the interdisciplinary team to monitor the medications’ side effects and the diameter of the remaining visceral aneurysms.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Rare Case of Abdominal Aortic and Multiple Visceral Aneurysms in a Pediatric Patient With PIK3CA Mutation and Vasculitis

Gomes,

Parodi,

Wood

et al. 2023

Vasc Endovascular Surg

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“…Estudo sobre a propriedade biomecânica de colos de aneurismas de cadáver também foi investigada (Queiroz, 2015). Outra linha de pesquisa do grupo, envolve testes biomecânicos, porém com dispositivo de insuflação, no qual foi avaliado AAA e aortas normais, caracterizando pressões e topografia das roturas neste modelo experimental (Gomes et al, 2021).…”

Section: Correlação Entre Energia De Deformação Do Espécime Da Parede...unclassified

“…Em terceiro lugar, enfatiza-se que o fenômeno rotura depende somente de uma pequena região no qual o estresse supera a força da parede arterial (Attarian et al, 2019). Considerando que o remodelamento parietal aneurismático não é linear e nem homogêneo, ou seja, o processo de degradação elástica e deposição de colágeno é muito desigual nos AAA, supõe-se que, é possível que haja pontos com maior fraqueza parietal e que podem ser responsáveis pela rotura aneurismática (Gomes et al, 2021).…”

Section: Correlação Entre Energia De Deformação Do Espécime Da Parede...unclassified

Correlação entre a morfologia de aneurismas da aorta abdominal e a biomecânica de fragmento da parede aneurismática

Constantin

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Primary resonance of a nonlinear fractional model for cerebral aneurysm at the circle of Willis

Cui

Wang

2022

Nonlinear Dyn

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Experimental Study of Rupture Pressure and Elasticity of Abdominal Aortic Aneurysms Found at Autopsy

Cited by 10 publications

References 16 publications

Rare Case of Abdominal Aortic and Multiple Visceral Aneurysms in a Pediatric Patient With PIK3CA Mutation and Vasculitis

Rare Case of Abdominal Aortic and Multiple Visceral Aneurysms in a Pediatric Patient With PIK3CA Mutation and Vasculitis

Correlação entre a morfologia de aneurismas da aorta abdominal e a biomecânica de fragmento da parede aneurismática

Primary resonance of a nonlinear fractional model for cerebral aneurysm at the circle of Willis

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