Abstract-It has some significance to study the influences of the droplet radius ratios on spray combustion due to the varying droplet radius ratios among droplets in the actual spray combustion. The volume of fluid (VOF) formulation is applied to model the combustion process of two decane droplets with different radiuses in a hot convective flow and the effects of the droplet ratios on burning rates of two droplets at fixed droplet center spacing are analyzed. The results show: when the burning rates of the front and the back droplets compare with that of the corresponding single droplet, the interaction reduces the burning rate of either droplet under different droplet radius ratios. For the same initial droplet radius, the burning rate of droplet located at the front is larger than that at the back under different droplet radius ratios. The results obtained provide some reference for the basic researches of spray combustion.