Prefabricated structures are widely used because of their advantages of energy savings, environmental protection, standardization, and universality. However, due to the complex structure of the joints, it is easy to make the joint installation difficult and the prefabricated column connection unreliable, and further lead to the poor seismic performance of the structure. Therefore, a new type of dry sleeve joint with double screw sleeve without support is proposed, and the seismic performance and influencing factors of the new dry-sleeve-joint prefabricated column are studied. This study encompasses seven reinforced concrete columns characterized by cross-sectional dimensions of 600 mm × 600 mm. Among these, five specimens feature a novel dry sleeve connection, while the remaining two specimens were entirely cast-in-place. Low-cycle reversed loading experiments were conducted on all specimens to analyze and compare the damage patterns, hysteresis curves, skeleton curves, displacement ductility, energy dissipation capacity, and ultimate bearing capacity between precast and cast-in-place columns. Several parameters, including fabrication method, axial compression ratio, longitudinal reinforcement diameter, and hoop spacing, were examined. The findings demonstrated that the calculated-to-tested ratio of the ultimate bearing capacity for the prefabricated specimens was determined to be 0.62, indicating a high level of safety. The displacement ductility coefficient for each specimen ranged from 2.43 to 3.31, while the ultimate drift ratio was within the range of 1/41 to 1/33, satisfying the specified requirements for seismic performance. However, the hysteresis curve of the prefabricated specimens exhibited a pinching effect, which may be related to the existence of a weak layer on the joint surface of the post-cast section. In general, the shape of the new dry sleeve is maintained in the test, the connection form can effectively transfer the force, and the longitudinal bars can be strained and yield when the prefabricated column reaches the peak load. The new type of dry sleeve connection can be used for longitudinal reinforcement connection of reinforced concrete columns with seismic design.