This study investigates the effectiveness of Microbially Induced Calcite Precipitation (MICP) technology in enhancing the stability of aeolian sand. Applying MICP to desert sand samples from Kashi, Xinjiang, the results demonstrated significant structural stability and erosion resistance in treated soils during wind erosion tests. Particularly after 14 days of treatment, the soil samples exhibited optimal wind erosion resistance and surface crust strength. Additionally, the formation of calcite significantly improved the soil’s penetration strength and wind erosion resistance, with SEM analysis confirming that calcite “bridges” between soil particles enhanced inter-particle bonding. Environmental impact assessments indicated that MICP technology is not only environmentally friendly but also effectively reduces the risk of soil environmental pollution. These findings validate the potential application of MICP technology in enhancing the stability and environmental adaptability of aeolian sand.