Due to the high cylinder pressure and high-performance requirements, the silicone oil damper of an inline six-cylinder diesel generator needs to be optimized to reduce the crankshaft stress. The centralized mass method was used to simplify the crankshaft system. A multi-body dynamic model was established, and the crankshaft stress and torsional vibration amplitude were simulated. The results show that the excessive shear stress at generator crank pin 5 is due to the resonance between the first-order intrinsic frequency of the shaft system and the 3rd harmonic torsional vibration. The shear stress was analyzed for different damper thicknesses and stiffnesses, and it was found that the shear stress at crank pin 5 was minimized when the damper thickness was 60 mm and the torsional stiffness was 250,000 N·m/rad. The torsional amplitudes at different speeds and frequencies were measured in the bench test, and the results were consistent with the calculations. The designed silicone oil torsional damper meets the requirements of the 2000-hour bench test.