Experimentally measured phonon spectrum of microtubules

Aslam, Arooj; Prodan, Camelia

doi:10.1088/1361-6463/ab4bfb

Cited by 2 publications

(1 citation statement)

References 18 publications

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“…This work focuses on models for the Equation Of State (EOS) for the detonation products of the High Explosive (HE) PBX 9501 1 using a functional form proposed by Davis [2–4]. This Davis Products functional form has changed slightly over time and in this work we will be using the functions as defined in [5]. One of the most important properties of an explosive is the speed at which an unsupported detonation wave can propagate through a charge of infinite diameter.…”

Section: Introductionmentioning

confidence: 99%

Calibration and uncertainty quantification for Davis Equation of State models for the High Explosive PBX 9501 products

Andrews,

Leiding,

Thrussell

et al. 2024

Propellants Explo Pyrotec

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This paper investigates the uncertainty in the parameters used in the calibration of an Davis Equation Of State (EOS) for the detonation products of the High Explosive PBX 9501. The procedure sought to make use of all available information about this HE to inform the best set of calibration parameters as well as the uncertainty in these parameters. The procedure made use of historical experimental data, the results from thermo‐chemical modeling as well as data on the best isentrope function fit to cylinder test experimental data. Combining all these heterogeneous data sources together in a Bayesian calibration, yielded a posterior mean and covariance. Sampling from the posterior distribution and evaluating an important Quantity Of Interest (QOI) in the EOS model, the detonation speed of a one‐inch rate stick, produced a distribution which showed variations which were in agreement with experiments. The uncertainty in the EOS was reported as eleven sets of model calibrations which spanned the range of this QOI.

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Section: Introductionmentioning

confidence: 99%

Calibration and uncertainty quantification for Davis Equation of State models for the High Explosive PBX 9501 products

Andrews,

Leiding,

Thrussell

et al. 2024

Propellants Explo Pyrotec

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Coupling of electrodynamic fields to vibrational modes in helical structures

Farhi

Dogariu

2021

Phys. Rev. A

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Helical structures like alpha helices, DNA, and microtubules have profound importance in biology. It has been suggested that these periodic arrangements of the constituent units could support collective excitations similarly to crystalline solids, which display a continuous spectrum and localized excitations. Here, we examine the interaction between such constructs and oscillating dipoles, and evaluate the role of the helical structure in the coupling between electrodynamic fields and phonons. Based on an eigenfunction analysis, we found that the helical configuration couples the azimuthal and axial degrees of freedom of the modes, which, in turn, leads to a discrete spectrum and delocalized excitations. Quasistatic eigenpermittivities are usually negative but we show here that in the case of anisotropic structures with cylindrical symmetry they are positive. This suggests a strong electrodynamic response in naturally occurring structures such as microtubules. The new type of dielectric quasistatic resonances identified here may help explain the role of electrodynamic fields in the diverse functionality of cytoskeletal microtubules in the cellular environment.Microtubules (MTs) are tubular helical structures that self-assemble from their constituent tubulin-protein units. MTs are critical for the development and maintenance of the cell shape, transport of vesicles and other components throughout cells, cell signaling, division, and mitosis. Because of their distribution of charges and the large dipole moments associated with tubulins [1], the microtubules have unique electric properties, which may affect the interactions with surrounding molecules, also beyond the common shortrange Coulomb and van der Waals interactions [2].

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Experimentally measured phonon spectrum of microtubules

Cited by 2 publications

References 18 publications

Calibration and uncertainty quantification for Davis Equation of State models for the High Explosive PBX 9501 products

Calibration and uncertainty quantification for Davis Equation of State models for the High Explosive PBX 9501 products

Coupling of electrodynamic fields to vibrational modes in helical structures

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