Experimentelle Studien zur Expositionsprophylaxe der Poliomyelitis

Bingel, K. F.; H, Engelhardt

doi:10.1007/bf02149206

Cited by 2 publications

(1 citation statement)

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“…As infected rodents excreted virus for some time, and experimental infection was successful by the oral route and by contact, it was suggested that contamination of food may be a natural method of transmission (Kilham et al, 1956a;Vanella et al, 1956). The long survival of the virus in vitro (Dick, 1948;Bingel and Engelhardt, 1953) would facilitate oral transmission.…”

Section: Discussionmentioning

confidence: 99%

A VIRUS OF THE ENCEPHALOMYOCARDITIS GROUP FROM A WATER‐RAT, HYDROMYS CHRYSOGASTER, IN NORTH QUEENSLAND

Pope

1959

Aust J Exp Biol Med

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A virus, referred to as the Innisfail strain, was isolated by mouse inoculation horn a naturally Infected water-rat, Hydromys chrysogaster, captured in north Queensland, Australia. It was shown to be indistinguishable from the EMC vims of Helwig and Schmidt by cross-neutralization and cross-complement fixation tests, and was considered to belong to the EMC group of viruses.Mice and guinea-pigs were highly susceptible. Rats showed signs of paralysis, but usually survived. Rabbits and three-day-old chickens were resistant.Infection of mice was characterised by paralysis and death in 2-3 days, and encephalitis and myositis were the prominent histopathological features. Heavily infected guinea-pigs died within 3-7 days, with encephalitis and seveie macroscopic myocarditis. This is believed to be the first report of natural infection with a virus of the EMC group in Australia.Toxoplasma was also isolated from the water-rat, making a new host record.

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Section: Discussionmentioning

confidence: 99%