The sensitivity of moving particle semi-implicit (MPS) simulations to numerical parameters is investigated in this study. Although the verification and validation (V&V) are important to ensure accurate numerical results, the MPS has poor performance in convergences with a time step size. Therefore, users of the MPS need to tune numerical parameters to fit results into benchmarks. However, such tuning parameters are not always valid for other simulations. We propose a practical numerical condition for the MPS simulation of a two-dimensional wedge slamming problem (i.e., an MPS-slamming condition). The MPS-slamming condition is represented by an MPS-slamming number, which provides the optimum time step size once the MPS-slamming number, slamming velocity, deadrise angle of the wedge, and particle size are decided. The simulation study shows that the MPS results can be characterized by the proposed MPS-slamming condition, and the use of the same MPS-slamming number provides a similar flow.