Expert Opinion: Efficacy of superficial chemical peels in active acne management – what can we learn from the literature today? Evidence‐based recommendations

Dréno, Brigitte; Fischer, T C; Perosino, E; Poli, F.; Viera,; Rendon, MI; Ds, Berson; Cohen, José L.; Roberts, W. R.; Starker, Isaac; Wang, B

doi:10.1111/j.1468-3083.2010.03852.x

Cited by 65 publications

(57 citation statements)

References 23 publications

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“…Other two studies evaluated the efficacy of GA on comedonic acne and showed improvement in retentional lesions after 3 months (Table 3). 11,12 Both studies confirmed that a minimal adverse event was reported on 97% of patients who showed no any complaints. A study by Kessler et al found that both GA and SA were similarly effective in treatment of acne vulgaris with minimal adverse events reported by SA.…”

Section: Resultsmentioning

confidence: 71%

Efficacy and safety of superficial chemical peeling in treatment of active acne vulgaris

Al-Talib

Al-Khateeb

Hameed

et al. 2017

An. Bras. Dermatol.

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Acne vulgaris is an extremely common condition affecting the pilosebaceous unit of the skin and characterized by presence of comedones, papules, pustules, nodules, cysts, which might result in permanent scars. Acne vulgaris commonly involve adolescents and young age groups. Active acne vulgaris is usually associated with several complications like hyper or hypopigmentation, scar formation and skin disfigurement. Previous studies have targeted the efficiency and safety of local and systemic agents in the treatment of active acne vulgaris. Superficial chemical peeling is a skin-wounding procedure which might cause some potentially undesirable adverse events. This study was conducted to review the efficacy and safety of superficial chemical peeling in the treatment of active acne vulgaris. It is a structured review of an earlier seven articles meeting the inclusion and exclusion criteria. The clinical assessments were based on pretreatment and post-treatment comparisons and the role of superficial chemical peeling in reduction of papules, pustules and comedones in active acne vulgaris. This study showed that almost all patients tolerated well the chemical peeling procedures despite a mild discomfort, burning, irritation and erythema have been reported; also the incidence of major adverse events was very low and easily manageable. In conclusion, chemical peeling with glycolic acid is a well-tolerated and safe treatment modality in active acne vulgaris while salicylic acid peels is a more convenient for treatment of darker skin patients and it showed significant and earlier improvement than glycolic acid

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Section: Resultsmentioning

confidence: 71%

Efficacy and safety of superficial chemical peeling in treatment of active acne vulgaris

Al-Talib

Al-Khateeb

Hameed

et al. 2017

An. Bras. Dermatol.

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“…Active ingredients in chemical peels, such as salicylic acid and glycolic acid, work by decreasing the connections between keratinocytes, thereby leading to desquamation [144]. Salicylic acid also decreases activity of the arachidonic acid pathway, thereby decreasing perilesional inflammation [145].…”

Section: Discussionmentioning

confidence: 99%

Optimizing Non-Antibiotic Treatments for Patients with Acne: A Review

Canavan

Chen

Elewski

2016

Dermatol Ther (Heidelb)

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Acne is a very common non-infectious skin condition that is frequently treated in dermatological practices. Because acne is often chronic and may persist for years, safe and effective long-term maintenance therapy is often required. Given the increasing frequency of antibiotic-resistant bacteria and the gravity of the consequences of this trend, it behooves dermatologists to maximize use of non-antimicrobial therapy when treating acne. In this review of the literature we present data regarding the efficacy and appropriate use of non-antimicrobial treatments for acne. A variety of topical and oral treatment options exist that can be used in a step-wise manner according to the patients’ severity and therapeutic response. Non-antimicrobial treatments can be highly efficacious at controlling acne, especially when used as maintenance therapy. While antibiotics have a role in acne treatment, they should not be used as monotherapy, and lengthy courses of antibiotic use are discouraged.

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“…Notably, no comparative studies of peeling agents against conventional acne medications have been performed. [58,59] …”

Section: Synergistic Topical Combinationsmentioning

confidence: 98%

What′s new in the management of acne?

Arshdeep¹,

De²

2013

Indian J Dermatol Venereol Leprol

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Expert Opinion: Efficacy of superficial chemical peels in active acne management – what can we learn from the literature today? Evidence‐based recommendations

Abstract: In the future, further study is needed to determine the best use of chemical peels in this indication.

Cited by 65 publications

References 23 publications

Efficacy and safety of superficial chemical peeling in treatment of active acne vulgaris

Efficacy and safety of superficial chemical peeling in treatment of active acne vulgaris

Optimizing Non-Antibiotic Treatments for Patients with Acne: A Review

What′s new in the management of acne?

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