William Uttal’s The New Phrenology (2001), although published more than a decade ago, remains a fundamental essay concerning the conceptual and methodological shortcomings of the scientific endeavors favoring the concept of localization (as opposed to universalization) of psychological functions in the brain. The book conveys a strong message in which the author explains that the efforts made to localize psychological entities in the brain are flawed for two main reasons: One is associated with the fact that there is no conclusive evidence that our mind can be divided into single modules, and the other is related to the difficulties that bedevil the possible mapping of mental functions and brain regions, especially due to the nonlinear interactions between both. By revisiting this book, the intention was to highlight the author’s position concerning the philosophical, conceptual, and technical issues underlying the associations between brain-related physiological signals and psychological faculties.