The chloride diffusion coefficients of different water-binder ratio high performance concrete (HPC) subjected to different one-way loads,freeze-thaw cycles and different standard curing ages were measured by electro-migration (RCM) tests and the results were analyzed. The test results indicate that with the increase of one-way load, its influence on the chloride permeability of different water-binder ratio HPC rises in the same proportion. The influence of the curing age on the chloride permeability of HPC will decrease with the reduction of the water-binder ratio of HPC. Under the same freeze-thaw cycle conditions, the relationships between chloride diffusion coefficients of different water-binder ratio HPC and curing ages are nearly suitable to power function.