Exploiting the immune system in hepatic tumor targeting: Unleashing the potential of drugs, natural products, and nanoparticles

Hsu, Chou-Yi; Mustafa, Mohammed Ahmed; Kumar, Ashwani; Pramanik, Atreyi; Sharma, Rajiv; Mohammed, Faraj; Jawad, Israa Abed; Mohammed, Imad Jasim; Alshahrani, Mohammad Y.; Ali khalil, Noor Alhuda Mohammad; Shnishil, Ali Turki; Abosaoda, Munther Kadhim

doi:10.1016/j.prp.2024.155266

Cited by 2 publications

(1 citation statement)

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“…They may activate or enhance the immune system, making it more effective in identifying and clearing tumor cells. This immune regulatory effect may include multiple mechanisms, such as enhancing T cell-mediated toxicity, promoting natural killer cell activity, and regulating immunosuppressive factors in the tumor microenvironment [168]. These mechanisms of action indicate that natural products have potential therapeutic value in inhibiting the development of HCC and have become important candidate drugs for studying immunotherapy and targeted therapy.…”

Section: Discussionmentioning

confidence: 99%

Research progress on natural products against hepatocellular carcinoma

ZHANG,

LI,

MAO

2024

BIOCELL

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Hepatocellular carcinoma (HCC) remains a prevalent and challenging malignancy globally, characterized by its numerous causal factors and generally unfavorable prognosis. In the relentless pursuit of effective treatment modalities, natural products have emerged as a promising and relatively non-toxic alternative, garnering significant interest. The integration of natural products with contemporary medical research has yielded encouraging therapeutic outcomes in the management of HCC. This review offers a comprehensive overview of the causal factors underlying HCC, and the diverse treatment options available, and highlights the advancements made by natural products in anti-HCC research.Particularly, we provide an outline of the various types of natural products, their corresponding nomenclature, target molecules, and mechanisms of action that exhibit anti-HCC activities. Natural products are anticipated to play a pivotal role in future comprehensive treatment plans for liver cancer, potentially offering patients improved survival rates and an enhanced quality of life.

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Section: Discussionmentioning

confidence: 99%

Research progress on natural products against hepatocellular carcinoma

ZHANG,

LI,

MAO

2024

BIOCELL

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Female Infertility: Exploring Biological Causes and Advanced Therapeutic Approaches

Dalis

2024

acopen

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Female infertility is a complex subject with numerous medical factors that are potentially devastating to a woman’s fertility. It is caused by conditions such as hormonal imbalances, structural anomalies and genetic susceptibility. In the present review, focus will be made on the understanding of the biological factors of female infertility and presentation of recent developments in medical management, medical treatments, assisted reproductive technology and molecular and developmental biology. Thus, the goal of this paper is to improve knowledge and practice considerations regarding female infertility by presenting a broad perspective. Highlights: Causes: Hormonal, structural, genetic factors affect fertility. Advances: Medical treatments, assisted reproduction, molecular biology progress. Goal: Enhance knowledge and practices on female infertility management. Keywords: Infertility in women, Women’s reproductive system, Endocrine disorders, IVF treatment, Gene therapy

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Exploiting the immune system in hepatic tumor targeting: Unleashing the potential of drugs, natural products, and nanoparticles

Cited by 2 publications

References 270 publications

Research progress on natural products against hepatocellular carcinoma

Research progress on natural products against hepatocellular carcinoma

Female Infertility: Exploring Biological Causes and Advanced Therapeutic Approaches

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