Moonpool-type floaters were initially proposed for applications such as artificial islands or as protecting barriers around a small area enabling work at the inner surface to be carried out in relatively calm water. In recent years, a growing interest on such structures has been noted, especially in relation to their use as heaving wave energy converters or as oscillating water column (OWC) devices for the extraction of energy from waves. Furthermore, in the offshore marine industry, several types of vessels are frequently constructed with moonpools. The present paper deals with the hydrodynamics of bottomless cylindrical bodies having vertical symmetry axis and floating in a water of finite depth. Two computation methods were implemented and compared: a theoretical approach solving analytically the corresponding diffraction problem around the moonpool floater and a computational fluid dynamics (CFD) solver, which considers the viscous effects near the sharp edges of the body (vortex shedding) as non-negligible. Two different moonpool-type configurations were examined, and some interesting phenomena were discussed concerning the viscous effects and irregularities caused by the resonance of the confined fluid.