Exploiting the mechanical bond for molecular recognition and sensing of charged species

Abstract

This review presents progress in the field of MIM hosts for ion recognition and sensing since 2014, focusing on the synthetic approaches employed and mechanisms of host–guest binding and detection.

Rotaxane CoII Complexes as Field-Induced Single-Ion Magnets

“…Interlocked molecules, [1][2][3][4][5] such as rotaxanes and catenanes, contain cavities within which donor atoms can be positioned to bind metal ions. [6][7][8][9][10][11][12][13] Indeed, some of the first observations of the properties of the mechanical bond, including its ability to kinetically stabilize metal complexes, 6,[14][15][16][17][18] were made by Sauvage and co-workers over 30 years ago. [19][20][21] More recently, 22 we demonstrated that rotaxanebased ligands can be used to produce complexes the non-interlocked equivalent of which are inaccessible, including examples reminiscent of the distorted "entatic states" of metalloproteins, 23,24 suggesting that interlocked ligands could allow engineering of the properties of metal ions.…”

Rotaxane CoII Complexes as Field‐Induced Single‐Ion Magnets

“…Interlocked molecules[ 1 , 2 , 3 , 4 , 5 ] contain cavities within which donor atoms can be positioned to bind metal ions. [ 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 ] Indeed, some of the first observations of the properties of the mechanical bond, including its ability to kinetically stabilize metal complexes,[ 6 , 14 , 15 , 16 , 17 , 18 ] were made by Sauvage and co‐workers over 30 years ago. [ 19 , 20 , 21 ] More recently, [22] we demonstrated that rotaxane‐based ligands can be used to produce complexes the non‐interlocked equivalent of which are inaccessible, including examples reminiscent of the distorted “entatic states” of metalloproteins,[ 23 , 24 ] suggesting that interlocked ligands could allow engineering of the properties of metal ions.…”

Rotaxane CoII Complexes as Field‐Induced Single‐Ion Magnets

“…Interlocked molecules [1–5] contain cavities within which donor atoms can be positioned to bind metal ions [6–13] . Indeed, some of the first observations of the properties of the mechanical bond, including its ability to kinetically stabilize metal complexes, [6, 14–18] were made by Sauvage and co‐workers over 30 years ago [19–21] .…”