Exploration biologique des drogues illicites et des médicaments psychotropes en milieu professionnel

Mura, Patrick; Saussereau, Élodie; Brunet, Bertrand; Goullé, Jean-Pierre

doi:10.1016/j.pharma.2012.03.002

Cited by 8 publications

(4 citation statements)

References 58 publications

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“…Polymerase chain reaction (PCR) testing is available to police to identify where specific C sativa samples came from in order to assist with forensic studies and investigations (87). In addition to urine as well as blood testing, saliva and hair testing for cannabis are possible – the latter for evaluation of chronic cannabis exposure (88, 89). …”

Section: Cannabis Lab Testingmentioning

confidence: 99%

Marijuana: Current Concepts†

Greydanus¹,

Hawver²,

Greydanus³

et al. 2013

Front. Public Health

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Marijuana (cannabis) remains a controversial drug in the twenty-first century. This paper considers current research on use of Cannabis sativa and its constituents such as the cannabinoids. Topics reviewed include prevalence of cannabis (pot) use, other drugs consumed with pot, the endocannabinoid system, use of medicinal marijuana, medical adverse effects of cannabis, and psychiatric adverse effects of cannabis use. Treatment of cannabis withdrawal and dependence is difficult and remains mainly based on psychological therapy; current research on pharmacologic management of problems related to cannabis consumption is also considered. The potential role of specific cannabinoids for medical benefit will be revealed as the twenty-first century matures. However, potential dangerous adverse effects from smoking marijuana are well known and should be clearly taught to a public that is often confused by a media-driven, though false message and promise of benign pot consumption.

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Section: Cannabis Lab Testingmentioning

confidence: 99%

Marijuana: Current Concepts†

Greydanus¹,

Hawver²,

Greydanus³

et al. 2013

Front. Public Health

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“…Quoi qu'il en soit, ces techniques de confirmation, complexes et longues, restent du domaine du biologiste et ne seront pas abordées ici. Citons enfin l'utilisation de spots de sang séchés, obtenus par une simple piqûre au bout du doigt, faciles à transporter et à conserver, et dont l'analyse par des techniques chromatographiques couplées à la spectrométrie de masse en tandem donne des résultats très prometteurs [21]. L'utilisation de la salive, longtemps controversée du fait du risque élevé de faux positifs pour les cannabinoïdes, a béné-ficié de progrès technologiques récents et sa fiabilité est meilleure actuellement [22,23].…”

Section: Aspects Techniquesunclassified

Dépistage de la consommation de substances psychoactives en milieu professionnel : enjeux techniques, éthiques et réglementaires

Tuchtan¹,

Bartoli²,

Lehucher-Michel³

et al. 2014

Archives des Maladies Professionnelles et de l'Environnement

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“…This is particularly frustrating because of the current lack of a common framework or established guidelines regarding the use of BDZ in the workplaces (Brcak et al, 2018 ; Kowalski-McGraw et al, 2018 ; Nkyekyer et al, 2018 ), and/or optimum prescribing practice that may minimize their adverse impact on an individual's injury risk. For example, even in countries whose legislation on health and safety at work does include workplace drug testing, BDZ are usually not included in the screening tests (Kazanga et al, 2012 ; Mura et al, 2012 ; Rosso et al, 2017 ). However, as the common European framework requires the employer to ban drugs at work if there is a considerable danger, while the employee should be in a state that does not endanger himself or others, characterizing the actual risk of occupational injuries in BDZ users may significantly contribute to the daily practice of Occupational Physicians (Pierce, 2012 ).…”

Section: Introductionmentioning

confidence: 99%

Occupational Injuries and Use of Benzodiazepines: A Systematic Review and Metanalysis

Garbarino

Lanteri

Bragazzi

et al. 2021

Front. Hum. Neurosci.

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Background: Benzodiazepines have been widely used in clinical practice for over four decades and continue to be one of the most consumed and highly prescribed class of drugs available in the treatment of anxiety, depression, and insomnia. The literature indicates that Benzodiazepine users at a significantly increased risk of Motor Vehicle accidents compared to non-users but the impact on injuries at workplace is not well-defined. We aimed to investigate whether use of benzodiazepine is associated with increased risk of occupational injuries (OI).Methods: PubMed, Embase, and Scopus databases were searched. A meta-analysis was performed to calculate odds ratio (OR) and 95% confidence interval (CI) among case controls, cross-sectional studies, either questionnaire or laboratory exams based.Results: A total of 13 studies met inclusion criteria, involving 324,168 OI from seven different countries, with an estimated occurrence of benzodiazepine positivity of 2.71% (95% CI 1.45–4.98). A total of 14 estimates were retrieved. Of them, 10 were based on laboratory analyses, three on institutional databases, while one study was based on questionnaires. Regarding the occupational groups, three estimates focused on commercial drivers (0.73%, 95% CI 0.12–4.30), that exhibited a reduced risk ratio for benzodiazepine positivity compared to other occupational groups (RR 0.109, 95% CI 0.063–0.187). Eventually, no increased risk for benzodiazepine positivity was identified, either from case control studies (OR 1.520, 95% CI 0.801–2.885, I2 76%), or cross sectional studies, when only laboratory based estimates were taken in account (OR 0.590, 95% CI 0.253–1.377, I2 63%).Conclusions: Even though benzodiazepines have the potential to increase injury rates among casual and chronic users, available evidence are insufficient to sustain this hypothesis, particularly when focusing on laboratory-based studies (i.e., studies the characterized the benzodiazepine immediately before the event).

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Exploration biologique des drogues illicites et des médicaments psychotropes en milieu professionnel

Cited by 8 publications

References 58 publications

Marijuana: Current Concepts†

Marijuana: Current Concepts†

Dépistage de la consommation de substances psychoactives en milieu professionnel : enjeux techniques, éthiques et réglementaires

Occupational Injuries and Use of Benzodiazepines: A Systematic Review and Metanalysis

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