2018
DOI: 10.1016/j.thromres.2017.12.021
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Exploration of adherence and patient experiences with DOACs one year after switching from vitamin-K antagonists- insights from the switching study

Abstract: VTE patients prioritised anticoagulation over other therapies whereas AF patients did not. All participants reported high levels of adherence to DOACs. Patients derived confidence from long-term management in specialist anticoagulation clinics stating a preference to be managed in such a service.

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Cited by 20 publications
(26 citation statements)
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“…Second, our study specifically focused on patients who switched from a VKA to a DOAC, whereas in other observational studies only oral anticoagulant (OAC)‐naïve patients or a combination of OAC‐naïve and OAC‐experienced patients were included. We also found a high anticoagulant adherence rate among VKA‐experienced patients in the SFK database, which was also described in other studies . This might be caused by a higher awareness of the importance of therapy adherence in patients with a history of anticoagulant monitoring.…”
Section: Discussionsupporting
confidence: 87%
“…Second, our study specifically focused on patients who switched from a VKA to a DOAC, whereas in other observational studies only oral anticoagulant (OAC)‐naïve patients or a combination of OAC‐naïve and OAC‐experienced patients were included. We also found a high anticoagulant adherence rate among VKA‐experienced patients in the SFK database, which was also described in other studies . This might be caused by a higher awareness of the importance of therapy adherence in patients with a history of anticoagulant monitoring.…”
Section: Discussionsupporting
confidence: 87%
“…Therefore, the increasing use of DOAC therapy might be expected to continue. It is unclear whether adherence to OAC may be improved by use of DOACs with conflicting evidence . There is still a concern that less frequent interaction with healthcare professionals, in a setting such as a warfarin clinic, may have unintended health consequences for a largely elderly population on OAC.…”
Section: Discussionmentioning
confidence: 99%
“…It is unclear whether adherence to OAC may be improved by use of DOACs with conflicting evidence. 31,39 There is still a concern that less F I G U R E 1 Anticoagulant prescribing trends 2010-2017 for general medical scheme eligible patients frequent interaction with healthcare professionals, in a setting such as a warfarin clinic, may have unintended health consequences for a largely elderly population on OAC. For example, monitoring of renal function is recommended by guidelines, 16 but this may not occur in the hectic setting of primary care.…”
Section: Discussionmentioning
confidence: 99%
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