Exploration of avocado by-products as natural sources of bioactive compounds

Tremocoldi, Maria Augusta; Rosalen, Pedro Luiz; Franchin, Marcelo; Massarioli, Adna Prado; Denny, Carina; Daiuto, Érica Regina; Paschoal, Jonas Augusto Rizzato; Melo, Priscilla Siqueira; Alencar, Severino Matias de

doi:10.1371/journal.pone.0192577

Cited by 171 publications

(151 citation statements)

References 34 publications

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“…While MAE and UAE did not show significant differences ( p > .05) between the antioxidant indicators; maceration presented the lower FRAP, but the lipidic peroxidation inhibition was statistically equal ( p > .05) to UAE and MAE. Even though this is the first work reporting the comparison of different extraction methods on the biological activity of avocado peel phenolic extracts; the results are in good agreement with Tremocoldi et al (), Melgar et al () and Morais et al (), whereas, the antioxidant indicators here, were entirely satisfactory.…”

Section: Resultssupporting

confidence: 90%

“…Recently, it was reported the extraction of phenolics from avocado peel var. Hass yielded 63.5 mg GAE/g using the same solvent system for this study and sonicated for 15 min at room temperature (Tremocoldi et al, ). Alike, the application of pressurized liquids on avocado peel yielded 57 mg GAE/g with ethanol/water (50:50, v/v) at 200°C (Figueroa, Borrás‐Linares, Lozano‐Sánchez, Quirantes‐Piné, & Segura‐Carretero, ).…”

Section: Resultsmentioning

confidence: 99%

“…The recent studies about phenolic extraction from avocado by‐products employed the conventional maceration (Melgar et al, ; Torres et al, ) or less affordable non‐conventional methods (Figueroa, Borrás‐Linares, Lozano‐Sánchez, & Segura‐Carretero, ). Regarding UAE, it was performed in another study to characterize the phytochemicals of two varieties of avocado fruits and their by‐products (Tremocoldi et al, ). However, the optimal extracting parameters were not evaluated, consequently, is unknown the effect of sonication time and temperature for the maximum TPC recovery.…”

Section: Introductionmentioning

confidence: 99%

“…(Epi) Catechins, quercetin, hydroxycinnamic acids, chlorogenic acids, and its derivatives, as well as procyanidins A and B, are some of the main identified phenolics in avocado peel (Figueroa, Borrás-Linares, Lozano-Sánchez, Quirantes-Piné, & Segura-Carretero, 2018;Torres et al, 2018). Therefore, there is a growing interest in obtaining these extracts and the purified compounds to be used by the food industry as innocuous clean label ingredients (Rodríguez-Carpena, Morcuende, Andrade, et al, 2011;Tremocoldi et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

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Improvement of the polyphenol extraction from avocado peel by assisted ultrasound and microwaves

Trujillo-Mayol

Cespedes‐Acuña

Silva

et al. 2019

J Food Process Engineering

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Ultrasound (UAE) and microwave (MAE) are green technologies to assist in the extraction of polyphenols. The goals were to study the application of sonication temperature (40–60°C), time (15–60 min), microwave power (250–750 W) at 30–120 s; and to combine the principal factors of each method for the maximum recovery of total phenolics from avocado peel employing a response surface methodology. The phytochemical, biological, and feasibility characteristics of the hydroethanolic extracts were analyzed. The combination of 15 min of sonication followed by 95.1 s of microwaving were the optimal parameters to recover 166.3 ± 4.9 mg GAE/g dry matter, which was 1.3, 1.2, and 1.1 times higher than UAE, MAE, and maceration, respectively. Likewise, the U‐MAE was upper in yield (25.3 ± 0.6%), TPC (281.4 ± 0.2 mg GAE), TFC (62.0 ± 0.4 mg QuE), and TAC (4.8 ± 0.1 mg cyanidin‐3‐O‐glucoside) and DPPH, FRAP and LPO (779.1 ± 0.6, 167.0 ± 2.3 μg TEAC, 70.03 ± 0.62%, respectively) per gram of dry extract. All the extracts displayed antibacterial activity. The economic feasibility analysis indicated MAE to be highly effective when energy is less affordable, whereas, if the cost associated with the raw material is high, the U‐MAE is suitable. Practical Applications The extraction industry is moving fast into sustainable processes based on the implementation of ecologically friendly methods of extraction and the utilization of by‐products to obtain bioactive metabolites to be used in the food and pharmaceutical industries. The results here presented were meant to design efficiently extracting procedures. Hence, the correct selection of factors that affect the extraction such as sonication temperature as well as microwave power is vital to reduce the resource consumption; especially raw material and time. Moreover, the exploitation of by‐products as the avocado peel will reduce the negative impact on the environment and enhance the value chain of avocado production.

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Section: Resultssupporting

confidence: 90%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Improvement of the polyphenol extraction from avocado peel by assisted ultrasound and microwaves

Trujillo-Mayol

Cespedes‐Acuña

Silva

et al. 2019

J Food Process Engineering

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“…Nevertheless, regardless the benefits which are obtained by processing fruits by-products within food industry, current preliminary scientific evidence confirms that fruits waste can be considered as a valuable source of phytoconstituents for medicinal applications. Anti-inflammatory potential of avocado peel and seed extracts was reported to suppress the release of tumor necrosis factor-α and generation of nitric oxide in lipopolysaccharide-stimulated RAW264.7 macrophages (Tremocoldi et al, 2018). Gastroprotective activity was reported for avocado seeds extract against indomethacin-induced gastric ulcer in mice (Athaydes et al, 2019).…”

Section: Therapeutic Properties Of Active Compounds From Fruits By-prmentioning

confidence: 99%

Fruits By-Products – A Source of Valuable Active Principles. A Short Review

Fierăscu

Sieniawska

Orţan

et al. 2020

Front. Bioeng. Biotechnol.

111

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The growing demand for more sustainable, alternative processes leading to production of plant-derived preparations imposes the use of plants waste generated mainly by agri-food and pharmaceutical industries. These mostly unexploited but large quantities of plants waste also increase the interest in developing alternative approaches for sustainable production of therapeutic molecules. In order to reduce the amount of plant waste by further processing, different novel extraction techniques can be applied. Fruits and their industrial by-products are rich sources of different classes of compounds with therapeutic properties. The processed fruits waste can be reused and lead to novel pharmaceuticals, food supplements or functional foods. This review intends to briefly summarize recent aspects regarding the production of different active compounds from fruit by-products, and their therapeutic properties. The potential use of fruits by-products in different industries will be also discussed.

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