Vocational chemistry education plays a pivotal role in preparing students for critical roles in industries where chemical expertise is crucial. The ability to think critically is essential for success and innovation in fields such as pharmaceuticals and environmental science. This study examines the impact of active learning strategies in enhancing critical thinking abilities within vocational chemistry settings. Active learning strategies, including problem-based learning, simulations, and collaborative projects, have been shown to effectively promote higher-order cognitive skills and practical application of chemical knowledge. However, the adoption of these strategies faces significant challenges, including institutional barriers, lack of faculty readiness, and resource constraints. The current study discusses these obstacles in depth and explores potential solutions, such as curriculum reform and professional development programs, to facilitate the effective integration of active learning. The study also emphasizes the need for longitudinal research to assess the long-term benefits of active learning on students' career progression and suggests that future investigations explore the use of emerging technologies like AI and augmented reality to further enhance learning experiences. This study aims to guide curriculum developers and educators in effectively implementing active learning strategies, thus improving educational outcomes and better preparing students for professional success in the chemical industry.