Exploration of high-density lipoprotein cholesterol level and serum testosterone concentrations in adult males from NHANES, 2011----2016

Abstract

Past explores have shown the expected linkage between high-thickness lipoprotein cholesterol (HDL-C) and testosterone fixations, yet the relationship is as yet hazy and questionable among the more extensive male populace in the U.S. The target of this review is to survey the relationship between HDL-C focuses and serum testosterone in U.S. grown-up guys. Information for this populace based study were from the Public Wellbeing and Sustenance Assessment Overview (NHANES) traversing 2011-2016. In the wake of barring grown-up guys matured under 18 years of age and without serum testosterone or HDL-C information, the example enveloped 7,804 male subjects. Contrasted and grown-ups introducing standard HDL-C levels, people with lessened HDL-C fixations displayed diminished testosterone levels (P<0.01). In the fundamental univariable direct relapse examination, factors including age, BMI, HDL, hemoglobin, creatinine and uric corrosive were seen to have an opposite relationship with serum testosterone levels. In the multivariate straight relapse examination, lessening serum testosterone related with decreased HDL-C focuses (assessed testosterone rate difference: 0.36% per mg/dL, P<0.01). In responsiveness examinations that prohibited anomaly or outrageous worth, HDL-C level was emphatically related with testosterone focuses. All in all, this cross-sectional review demonstrated a positive linkage between HDL-C levels and serum testosterone focuses in grown-up guys, and further largescale planned examinations are fundamental for approval of the causality between HDL-C and testosterone.