Exploration of Inorganic Materials with Antiviral Properties

Pattnaik, Sushree; Chaudhury, Balamati; Mohapatra, Mamata

doi:10.1007/978-981-16-4372-9_4

Cited by 3 publications

(4 citation statements)

References 130 publications

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“…CuNPs have strong antioxidant potential, and fungus-mediated production is a viable way to take advantage of their positive benefits. Due to their unique physicochemical characteristics, they are effective scavengers of free radicals and ROS, resulting in antioxidant activity [40], [41]. Fungus-mediated synthesis offers a renewable and sustainable way of creating CuNPs with increased antioxidant potential.…”

Section: Antioxidant Properties Of Fungusmediated Cunpsmentioning

confidence: 99%

Development of copper nanoparticles and their prospective uses as antioxidants, antimicrobials, anticancer agents in the pharmaceutical sector

Tyagi

Arya

Mazumder

et al. 2023

Precision Nanomedicine

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In this study, we review the synthesis of copper nanoparticles (CuNPs) and their prospective uses as antioxidants, antimicrobials, and anticancer agents in the pharmaceutical sector. Copper nanoparticles could be created through a variety of methods, including chemical reduction, green synthesis, physical methods, electrochemical deposition, and the microemulsion method. These methods make it possible to precisely create nanoparticles with the necessary shapes, sizes, and surface properties, which in turn affect how well they perform biologically. CuNPs have strong antioxidant properties because they can scavenge reactive oxygen species (ROS) and prevent oxidative damage. In addition to their antioxidant properties, CuNPs show antibacterial activity against a number of microbes, including bacteria, fungi, and viruses. The potential of CuNPs as an anticancer agent has also been extensively investigated. These nanoparticles have toxic effects on a variety of cancer cell lines by inducing apoptosis, inhibiting cell proliferation, and preventing tumour angiogenesis. Because of their specific toxicity towards cancer cells while protecting normal cells, they provide the fascinating potential for tailored therapy to overcome multidrug resistance. CuNPs have also been studied in relation to their usage in medications. They may be utilised to improve drug delivery systems, wound healing, diagnostic imaging, immunotherapy, and anti-inflammatory and antioxidant effects. They can also be used to improve pharmaceutical stability, bioavailability, and provide controlled release. More research is needed to ensure their safety, enhance their synthesis processes, and explore their full potential in therapeutic situations

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Section: Antioxidant Properties Of Fungusmediated Cunpsmentioning

confidence: 99%

Development of copper nanoparticles and their prospective uses as antioxidants, antimicrobials, anticancer agents in the pharmaceutical sector

Tyagi

Arya

Mazumder

et al. 2023

Precision Nanomedicine

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show abstract

“…Furthermore, many of reports revealed that ZnO-NPs' ability to act as a disinfectant against the SARS-CoV-2 pathogen [51][52]. ZnO nanoparticles efficiently capture viral via a novel virostatic mechanism, preventing them from passing through corneal fibroblasts cell [53 ].Due to their potential to inactivate viruses, ZnO-NPs is a promising material for future usage as an anticoronavirus surface due to their ecologically friendly features, unique physical and chemical functionality…”

Section: Anti-surface Coating For Coronavirusmentioning

confidence: 99%

ZnO nanoparticles and their properties as surface coating materials against coronavirus: viewpoint

Idriss¹,

Habib²,

Alakhras³

et al. 2022

JOBM

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A pandemic of coronavirus infection is causing a significant public health hazard globally, putting millions of people at risk in an increasing amount of countries. Nanostructured materials have been recognized to be highly efficient against coronaviruses. ZnO nanoparticles possess unique features that enable to act as anti-bacterial and anti-viral. Hence, the aim of the current investigation is to produce zinc oxide nanoparticles and utilized as surface coating materials against COVID-19. Thermal decomposition has been utilized in this investigation to fabricate ZnO nanoparticles with crystallite of 41 and 55 nm. The study outcomes demonstrated that Zinc nanoparticles is a favorable material for future usage as an anti-coronavirus surface due to their ecologically friendly features and exceptional physical and chemical functionality.

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“…For that reason, research on alternative treatments that could lead to a reduction of the burden of this disease are of interest. Some approaches that have proven their effectiveness against PRRSV in vitro are plant extracts like Caesalpinia sappan [9], tea polyphenols [10], nanoparticles [11], carbon-based materials [12] or mycotoxins [13] among others. However, a number of these options, such as nanoparticles [11] or carbon-based materials, [12] are either difficult or costly to obtain or can lead to secondary effects when used long-term [13].…”

Section: Introductionmentioning

confidence: 99%

“…Some approaches that have proven their effectiveness against PRRSV in vitro are plant extracts like Caesalpinia sappan [9], tea polyphenols [10], nanoparticles [11], carbon-based materials [12] or mycotoxins [13] among others. However, a number of these options, such as nanoparticles [11] or carbon-based materials, [12] are either difficult or costly to obtain or can lead to secondary effects when used long-term [13]. Therefore, finding an alternative that can be used in swine industry that surpasses those obstacles while maintaining low production costs is the key for a successful and applicable product.…”

Section: Introductionmentioning

confidence: 99%

Effect of BIO-PLYTM, a Platelet-Rich Plasma Derived Biologic on PRRSV-2-Infected Macrophages

Frias-De-Diego

Gilbertie

Scholle

et al. 2022

Viruses

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Porcine Reproductive and Respiratory Syndrome (PRRS) is the one of the most devastating diseases impacting the swine industry worldwide. Control and prevention methods rely on biosafety measures and vaccination. As an RNA virus with a high rate of mutation, vaccines are only partially effective against circulating and newly emerging strains. To reduce the burden of this disease, research on alternative control methods is needed. Here, we assess the in vitro antiviral effect of a novel platelet-rich plasma-derived biologic termed BIO-PLYTM (for the BIOactive fraction of Platelet-rich plasma LYsate) from both swine and equine origin. Our results show that BIO-PLYTM significantly reduces the amount of PRRSV viral load determined by RT-qPCR and the number of infectious viral particles measured by TCID50 in infected porcine alveolar and parenchymal macrophages. This study also showed limited toxicity of BIO-PLYTM in vitro and aspects of its immunomodulatory capacity evaluating the regulation of reactive oxygen species and cytokines production in infected cells. Finally, this study presents promising data on the effect of BIO-PLYTM on other RNA viruses such as human A influenza viruses and coronavirus.

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Exploration of Inorganic Materials with Antiviral Properties

Cited by 3 publications

References 130 publications

Development of copper nanoparticles and their prospective uses as antioxidants, antimicrobials, anticancer agents in the pharmaceutical sector

Development of copper nanoparticles and their prospective uses as antioxidants, antimicrobials, anticancer agents in the pharmaceutical sector

ZnO nanoparticles and their properties as surface coating materials against coronavirus: viewpoint

Effect of BIO-PLYTM, a Platelet-Rich Plasma Derived Biologic on PRRSV-2-Infected Macrophages

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