Exploration of possible cell chirality using material techniques of surface patterning

Enlargement, Reduction, and Even Reversal of Relative Migration Speeds of Endothelial and Smooth Muscle Cells on Biomaterials Simply by Adjusting RGD Nanospacing

“…Properties of interfaces and surfaces of implanted biomaterials, such as biochemical composition, ligand organization, stiffness, viscoelasticity, topology, and even nanoscale cues, have been proved effective for triggering cell responses. − Among these, RGD (Arg–Gly–Asp) peptides can enhance cell–substrate interactions and can also regulate cell behaviors like adhesion, migration, proliferation, differentiation, dedifferentiation, etc. − In the present work, RGD peptides were used for surface modification to explore whether its nanospacing can regulate relative cell migration speeds among different cell types. ECs and SMCs were chosen as representative cell types.…”

Bioinspired silk fibroin materials: From silk building blocks extraction and reconstruction to advanced biomedical applications

“…From the solution or suspension of the extracted building blocks, RSF biomaterials with desired topological, stiffness, or chemical contrast features in 2D film or 3D scaffold could be feasibly constructed, and hence provided a powerful material platform for the study of cell-material interactions. This kind of study is quite important for understanding different material cues effect on cell behaviors, thus much valuable for the design, fabrication, and modification of effective biomaterials [ [118] , [119] , [120] , [121] , [122] , [123] ]. Based on the developed material fabrication and surface pattering technologies, some valuable cell-material interactions have been revealed via the RSF materials, which will be comprehensively summarized as follows.…”

Two-photon polymerization for 3D biomedical scaffolds: Overview and updates

“…By shrinking the size of the products, photolithography makes a leap forward in the manufacture of electronic components. However, both the traditional photolithography and other lithography techniques derived from or substituted for it, including dip-pen nanolithography (Ginger et al, 2004), capillary force lithography (Kim et al, 2001), nanoimprint lithography (Dvurechenskii and Yakimov, 2017;Schift, 2008), soft lithography (Geissler and Xia, 2004), transfer lithography (Yao et al, 2013;Yao et al, 2021) and others, are inherently twodimensional. Features currently available in 3D structures using these methods have not be comparable to what can be achieved in 2D (LaFratta et al, 2007).…”