2024
DOI: 10.1002/cbdv.202400910
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Exploration of the Mechanisms of Bu‐Yang‐Huan‐Wu Decoction in the Treatment of Diabetic Peripheral Neuropathy by Integrating of Serum Pharmacochemistry and Network Pharmacology

Peng‐Fei Chen,
Guang‐Xiao Huang,
Wen‐Ting Gu
et al.

Abstract: Diabetic peripheral neuropathy (DPN) is a significant and frequent complication of diabetes. Bu‐Yang‐Huan‐Wu Decoction (BHD) is a classic traditional Chinese herbal prescription that is commonly used in modern clinical practice for the effective treatment of DPN , but the underlying mechanism is not yet clearly defined. The chemical constituents of BHD were characterized by UPLC‐Q‐Orbitrap HR MS/MS, and a total of 101 chemical components were identified, including 30 components absorbed into blood. An interact… Show more

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