“…In silico analysis of isolated compounds obtained from the methanol extract of T crispa indicated that certain selective compounds have the potential to modify the activity of SARS-CoV-2 Mpro (Rakib et al, 2020). Additionally, another in silico study demonstrated that the tyramine-Fe complex of T crispa exhibits better potential anti-inflammatory activity compared to tyramine alone, aspirin, and ibuprofen (Widodo, 2021). However, it is important to exercise caution and not hastily conclude that in vitro or in silico activity implies improved clinical outcomes.…”