2024
DOI: 10.1021/acs.accounts.3c00781
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Exploring Aqueous Coordination Chemistry of Highly Lewis Acidic Metals with Emerging Isotopes for Nuclear Medicine

Jennifer N. Whetter,
Dariusz Śmiłowicz,
Eszter Boros

Abstract: Metrics & MoreArticle Recommendations CONSPECTUS: Nuclear medicine harnesses radioisotopes for the diagnosis and treatment of disease. While the isotopes 99m Tc and 111 In have enabled the clinical diagnosis of millions of patients over the past 3 decades, more recent clinical translation of numerous 68 Ga/ 177 Lu-based radiopharmaceuticals for diagnostic imaging and therapy underscores the clinical utility of metal-based radiopharmaceuticals in mainstream cancer treatment. In addition to such established rad… Show more

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