Exploring cyclopropylamine containing cyanopyrimidines as LSD1 inhibitors: Design, synthesis, ADMET, MD analysis and anticancer activity profiling

Ahmad Sheikh, Khursheed; Parveen, Darakhshan; Mumtaz Alam, M.; Azam, Faizul; Ahmed Khan, Mohammad; Akhter, Mymoona; Tasneem, Sharba; Meenu,; Parvez, Suhel; Imtiyaz, Khalid; Rizvi, Moshahid A.; Shaquiquzzaman, M.

doi:10.1016/j.bioorg.2024.107336

Bioorganic Chemistry

2024

DOI: 10.1016/j.bioorg.2024.107336

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Exploring cyclopropylamine containing cyanopyrimidines as LSD1 inhibitors: Design, synthesis, ADMET, MD analysis and anticancer activity profiling

Khursheed Ahmad Sheikh,

Darakhshan Parveen,

M. Mumtaz Alam

et al.

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Investigation of the anticancer potential of newly synthesized N4-substituted thiosemicarbazones: In silico and in vitro biological approaches

Singh,

Haribabu,

Moraga

et al. 2025

Journal of Molecular Structure

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Investigation of the anticancer potential of newly synthesized N4-substituted thiosemicarbazones: In silico and in vitro biological approaches

Singh,

Haribabu,

Moraga

et al. 2025

Journal of Molecular Structure

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Exploring cyclopropylamine containing cyanopyrimidines as LSD1 inhibitors: Design, synthesis, ADMET, MD analysis and anticancer activity profiling

Cited by 1 publication

References 41 publications

Investigation of the anticancer potential of newly synthesized N4-substituted thiosemicarbazones: In silico and in vitro biological approaches

Investigation of the anticancer potential of newly synthesized N4-substituted thiosemicarbazones: In silico and in vitro biological approaches

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