Virtual coupling (VC) is a train-centric next generation signalling system, which can enable multiple trains to operate in a formation just like one train or decouple separately on-the-run or at station flexibly or as planned. With the aim of optimizing the interdeparture train headway time, providing the variable capacity for diverse passenger demand, maximizing the passenger riding comfort degree, and minimizing passenger travel cost and train operation cost, the dynamic schedule for VC-enabled rail transit services is investigated with the multiagent simulation technique on NetLogo platform. Our contribution is mainly fourfold. First, VC-enabled rail transit entity for simulation is represented with the multiagent technique, including representation of train unit, train convoy, passenger attributes and behavior, and mathematical formula for calculation of the train operation cost and passenger travel cost, as well as passengers riding comfort degree are proposed. Second, the operational principles for flexible and self-organisingVC-enabled trains are defined. Third, the VC-enabled train-centric, passenger demand-driven, and agent-based simulation flow and algorithms are developed innovatively, which adopt the ergodic strategy for simulation by traversing each O-D pair demand along each route section over the rail transit network. Finally, we test and discuss the proposed methodology on the designed computational experiment on the NetLogo platform, and the simulation results series validated the effectiveness of the proposed methodology. The provided research can effectively support the VC-enabled platoon operation-oriented train service schedule for future study.