Exploring experiences of hypertrophic cardiomyopathy diagnosis, treatment, and impacts on quality of life among middle-aged and older adults: An interview study

Clinical course of adults with co-occurring hypertrophic cardiomyopathy and hypertension: A scoping review

“…One study focused on adults with apical HCM [ 28 ]; 2 focused on adults with obstructive HCM only [ 27 , 29 ], and the rest included adults with varied subtypes of HCM. Six studies defined hypertension and used Joint National Congress 7 (JNC7) criteria, systolic blood pressure (SBP) ≥140 mmHg, diastolic blood pressure (DBP) ≥ 90 mmHg, or taking anti-hypertensive medication [ 10 , 20 , 22 , 31 , 34 , 35 ]. Article details are presented in Table 1 .…”

“…Clinical profile characteristics of adults with co-occurring HCM and hypertension, compared to adults with HCM alone, are presented in Table 2 . Adults with co-occurring HCM and hypertension were consistently older across studies compared to those with HCM alone [ 10 , 22 , [31] , [32] , [33] , [34] , [35] ]. Co-occurring hypertension was more prevalent among Black adults, compared to White adults, with HCM, though only one study reported race [ 10 ].…”

“…Co-occurring hypertension was more prevalent among Black adults, compared to White adults, with HCM, though only one study reported race [ 10 ]. Hypertension prevalence was largely equally distributed by sex [ 31 , 32 , 34 , 35 ], though one study noted differences in prevalence by sex when age was stratified, there was a higher prevalence of hypertension in men age 37 (first quartile) and women age ≥ 75 (last quartile),in a cohort with a median age of 55 [ 8 ]. Adults with HCM and hypertension were more likely to have other comorbidities, including diabetes, obesity, and hyperlipidemia compared to adults with HCM alone [ 22 , [30] , [31] , [32] , 34 , 35 ].…”

“…Hypertension prevalence was largely equally distributed by sex [ 31 , 32 , 34 , 35 ], though one study noted differences in prevalence by sex when age was stratified, there was a higher prevalence of hypertension in men age 37 (first quartile) and women age ≥ 75 (last quartile),in a cohort with a median age of 55 [ 8 ]. Adults with HCM and hypertension were more likely to have other comorbidities, including diabetes, obesity, and hyperlipidemia compared to adults with HCM alone [ 22 , [30] , [31] , [32] , 34 , 35 ]. A minority of articles examined history of stroke/transient ischemic attack or renal function among their participants, though they found that adults with HCM and hypertension had worse renal function and more history of stroke/transient ischemic attack compared to those with HCM alone [ 22 , 31 , 32 , 35 ].…”

Clinical course and outcomes in adults with co-occurring hypertrophic cardiomyopathy and hypertension: a scoping review protocol

“…Hypertension can be a diagnostic confounder for HCM as it contributes independently to left ventricular hypertrophy, a diagnostic hallmark of HCM 3 11. Patients often experience prolonged paths to an HCM diagnosis navigating multiple layers of the healthcare system, including seeing a variety of providers and being misdiagnosed with other conditions, before reaching an HCM specialist 12. Emerging cardiac magnetic resonance imaging techniques are increasingly used to differentiate between HCM and hypertension, but such imaging may not be widely available in community settings 13 14.…”