The present study examined the emergence of innovative moments in Brief Integrative Psychotherapy based on Hill’s 3-stage model, in a small sample of clients. Innovative moments are markers of client change in which the problem or problems that have caused client suffering are challenged. Previous studies, with different models of psychotherapy, have supported the hypothesis that therapy sessions of recovered clients have more innovative moments than therapy sessions of unchanged clients. Moreover, it has been shown that the emergence of innovative moments in one session were better predictors of a symptom’s change in the following session than the other way around (i.e., a symptom’s change predicting innovative moments); nevertheless, little is known about the relations between innovative moment emergence in a given session and the subjective impact of that session from both client and therapist perspectives. The aim of the study was to examine the relations between innovative moments, on the one hand, and 3 session-by-session variables on the other: (1) symptomatic improvement, (2) session impact on the client, and (3) session impact, from the therapist’s point of view. Eight cases of 12-session Brief Integrative Psychotherapy were coded according to the Innovative Moments Coding System. Using a hierarchical linear model, we examined the associations between innovative moments, outcome improvement measured by the Outcome Questionnaire, and the session’s impact for both client and therapist measured by the Session Evaluation Questionnaire. Results showed that innovative moments and outcome improvement increased along treatment. Innovative moments did not predict outcome improvement in the following session but were predicted by the outcome improvement of the same session. Finally, associations were found between innovative moments and clients’ session impact ratings (positivity, smoothness, and depth) and therapists’ positivity ratings. These findings provide further empirical support for the hypothesis that innovative moments represent a transtheoretical phenomenon that seems to be valuable to both clients and therapists.