Exploring lncRNA Expression Patterns in Patients With Hypertrophied Ligamentum Flavum
Junling Chen,
Guibin Zhong,
Manle Qiu
et al.
Abstract:Objective: Hypertrophy ligamentum flavum (LFH) is a common cause of lumbar spinal stenosis, resulting in significant disability and morbidity. Although long noncoding RNAs (lncRNAs) have been associated with various biological processes and disorders, their involvement in LFH remains not fully understood.Methods: Human ligamentum flavum samples were analyzed using lncRNA sequencing followed by validation through quantitative real-time polymerase chain reaction. To explore the potential biological functions of … Show more
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