This research paper explores the integration of ChatGPT as a tool for interactive learning of numerical methods in a differential equations (DEs) course. DE course is crucial for engineering students to model real-world phenomena. However, many DE courses focus only on analytical solutions and neglect important numerical solutions. To overcome this gap, an active learning approach was adopted, where students were asked to select a real-life phenomenon in their field of interest, find an appropriate model to describe it using DEs, and subsequently solve DE numerically using various numerical methods. The authors allowed students to use ChatGPT to generate codes and learn how to adapt them to their personalized learning needs. The findings derived from the students’ survey responses demonstrated that ChatGPT significantly enhanced their interests and improved their coding skills. Students reported increased engagement and excitement in their learning journey with the integration of ChatGPT. By sharing this experience, we aim to inspire other educators to explore the potential of innovative technologies and instructional methods to enhance their own courses.