“…Since heavy quarks emerge essentially in early, hard processes, they witness the course of a heavy-ion collision -either as individual entities or subjects of dissociating and regenerating bound states [2,3,4]. Accordingly, the heavy-quark physics addresses such issues as charm (c,c) and bottom (b,b) dynamics related to transport coefficients [5,6,7,8,9] in the rapidly evolving and highly anisotropic ambient quark-gluon medium [10,11] as well as cc / bb states as open quantum systems [12,13,14,15]. The rich body of experimental data from LHC, and also from RHIC, enabled a tremendous refinement of our theoretical treatment which grew up on initiating ideas like "Mott mechanism and the hadronic to quark matter matter phase transition" [16], "J/ψ suppression by quark-gluon plasma formation" [17], "Dissociation kinetics and momentum dependent J/ψ suppression" [18], and "Statistical hadronization of charm in heavy ion collisions at SPS, RHIC and LHC" [19].…”