Background: Most nursing interns indicated they had experienced some form of workplace violence on clinical placement, which could be linked to higher adverse events. Prior researches have examined the effects of workplace violence on patient safety, but there have been very few explorations of whether workplace violence affects patient safety through professional identity and burnout among nursing interns.The purpose of this study is to test whether professional identity and professional burnout play mediating roles in the relationship of workplace violence and patient safety among nursing interns. Methods: Our study used a cross-sectional design. The study consisted of 466 nursing interns from three tertiary grade A hospitals in Shandong Province, China. The Chinese version of the Workplace Violence Scale, the Professional Identity Scale, the Chinese version of the Maslach Burnout Inventory-General Survey, the Patient Safety Behavior Scale were used to gather data. Descriptive analysis, t tests, analysis of variance, Pearson correlation, the serial multiple mediation analysis were used to analyze data.Results: Workplace violence, professional identity, professional burnout and patient safety were significantly correlated (p < 0.01). Workplace violence can not only have a direct positive impact on patient safety of the nursing interns (effect=-0.3280;SE=0.1492;95%CI: LL=-0.6212, UL=-0.0347), but also have an indirect impact on the patient safety through three paths: the independent mediating role of professional identity (effect=-0.3070;SE=0.1282;95%CI: LL=-0.6495, UL=-0.1399), the independent mediating role of professional burnout(effect=-0.1151;SE=0.